Antimicrobial opposition in N. gonorrhoeae remains a vital challenge to put a control over gonorrhea; gonococcal strains may be opposing to penicillin, tetracycline, fluoroquinolones and spectinomycin. Resistance to CDC-recommended doses of ofloxacin and ciprofloxacin go beyond 40% in some Asian countries, according to World Health Organization (WHO)Fluoroquinolone-resistant strains of N. gonorrhoeae have also been found in the Canada and the United States. The percentage of gonococcal isolates in Hawaii that are fluoroquinolone-resistant at present go beyond 13% and rising numbers of resistant strains have been acknowledged in the continent of United States.
Antimicrobial opposition in N. gonorrhoeae happens as plasmid-mediated resistance to tetracycline and penicillin, and chromosomally mediated opposition to penicillin, tetracycline, fluoroquinolones and spectinomycin,.
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